Short Answer 
The largest number in the sequence is 52,000, and the next whole number is 52,001. The sum of the third number (37,000) and the fourth number (819) is 37,819.
Step 1: Identify the Largest Number
Begin by examining the given sequence of numbers: 52,000, 45,000, 37,000, 819, 20, and 21. From these numbers, determine which one is the largest. In this case, the largest number is 52,000. To find a whole number that is larger, simply add one, resulting in 52,001.
Step 2: Locate the Third and Fourth Numbers
Next, identify the position of the third and fourth numbers in the sequence. Remember that counting starts from the first number in the list. The positions can be summarized as follows:
- Third number: 37,000
- Fourth number: 819
Step 3: Calculate Their Sum
The final step is to compute the sum of the third and fourth numbers you’ve identified. To do this, simply add them together:
- Calculation: 37,000 + 819 = 37,819
In conclusion, the whole number larger than the largest in the sequence is 52,001, and the sum of the third and fourth numbers is 37,819.